# D-Cycloserine Augmentation of Intermittent Theta Burst Stimulation (iTBS) in Depression (COGENT)

> **NCT05591677** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **The Alfred** · enrollment: 180 (estimated)

## Conditions studied

- Major Depressive Disorder

## Interventions

- **DRUG:** D-Cycloserine
- **DEVICE:** Intermittent Theta Burst Stimulation

## Key facts

- **NCT ID:** NCT05591677
- **Lead sponsor:** The Alfred
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2023-04-21
- **Primary completion:** 2026-05-29
- **Final completion:** 2026-05-29
- **Target enrollment:** 180 (ESTIMATED)
- **Last updated:** 2025-12-04

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05591677

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05591677, "D-Cycloserine Augmentation of Intermittent Theta Burst Stimulation (iTBS) in Depression (COGENT)". Retrieved via AI Analytics 2026-06-22 from https://api.ai-analytics.org/clinical/NCT05591677. Licensed CC0.

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