# A Novel Oral Synbiotic Formula in Reducing Advanced Adenoma Recurrence and Colorectal Neoplasia-related Bacterial Gene Markers

> **NCT05592886** · NA · RECRUITING · sponsor: **Chinese University of Hong Kong** · enrollment: 649 (estimated)

## Conditions studied

- Colorectal Neoplasms
- Colorectal Adenoma
- Colorectal Cancer
- Advanced Adenoma

## Interventions

- **OTHER:** SMT04 formula
- **OTHER:** Active placebo

## Key facts

- **NCT ID:** NCT05592886
- **Lead sponsor:** Chinese University of Hong Kong
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-12-15
- **Primary completion:** 2027-12-15
- **Final completion:** 2027-12-31
- **Target enrollment:** 649 (ESTIMATED)
- **Last updated:** 2025-08-01

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05592886

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05592886, "A Novel Oral Synbiotic Formula in Reducing Advanced Adenoma Recurrence and Colorectal Neoplasia-related Bacterial Gene Markers". Retrieved via AI Analytics 2026-06-29 from https://api.ai-analytics.org/clinical/NCT05592886. Licensed CC0.

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