# Transarterial Neoadjuvant Chemotherapy vs.Traditional Intravenous Chemotherapy For Locally Advanced Gastric Cancer With SOX+PD-1

> **NCT05593458** · PHASE3 · RECRUITING · sponsor: **Zhejiang University** · enrollment: 190 (estimated)

## Conditions studied

- Locally Advanced Gastric Carcinoma

## Interventions

- **DRUG:** Oxaliplatin by arterial infusion plus S-1
- **DRUG:** SOX neoadjuvant
- **DRUG:** Sintilimab neoadjuvant
- **PROCEDURE:** gastrectomy plus D2 lymph node dissection
- **DRUG:** SOX adjuvant, Sequential S-1
- **DRUG:** Sintilimab adjuvant

## Key facts

- **NCT ID:** NCT05593458
- **Lead sponsor:** Zhejiang University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-04-01
- **Primary completion:** 2026-06
- **Final completion:** 2026-12
- **Target enrollment:** 190 (ESTIMATED)
- **Last updated:** 2025-04-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05593458

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05593458, "Transarterial Neoadjuvant Chemotherapy vs.Traditional Intravenous Chemotherapy For Locally Advanced Gastric Cancer With SOX+PD-1". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05593458. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*