# Zoledronic Acid-loaded Bone Cement as a Local Adjuvant Therapy for Giant Cell Bone Tumor After Intralesional Curettage

> **NCT05595603** · PHASE2 · RECRUITING · sponsor: **Second Affiliated Hospital, School of Medicine, Zhejiang University** · enrollment: 153 (estimated)

## Conditions studied

- Giant Cell Tumor of Bone

## Interventions

- **PROCEDURE:** 4mg ZOL loaded gentamicin PMMA
- **PROCEDURE:** gentamicin PMMA

## Key facts

- **NCT ID:** NCT05595603
- **Lead sponsor:** Second Affiliated Hospital, School of Medicine, Zhejiang University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-03
- **Primary completion:** 2026-06-01
- **Final completion:** 2026-12-01
- **Target enrollment:** 153 (ESTIMATED)
- **Last updated:** 2023-03-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05595603

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05595603, "Zoledronic Acid-loaded Bone Cement as a Local Adjuvant Therapy for Giant Cell Bone Tumor After Intralesional Curettage". Retrieved via AI Analytics 2026-06-12 from https://api.ai-analytics.org/clinical/NCT05595603. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*