A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)

NCT05600426 · clinicaltrials.gov ↗

PHASE3

Phase

ACTIVE_NOT_RECRUITING

Status

53

Enrollment

OTHER

Sponsor class

Conditions

Severe Aplastic Anemia

Interventions

DRUG: cyclosporine
PROCEDURE: Matched Unrelated Donor Hematopoetic Stem Cell Transplant
DRUG: horse anti-thymocyte globulin (ATG)
DRUG: rabbit anti-thymocyte globulin (ATG)
DRUG: Methotrexate
DRUG: Fludarabine
DRUG: Cyclophosphamide
RADIATION: low-dose total body irradiation (TBI)
PROCEDURE: Immunosuppressive Therapy (IST)

Sponsor

Boston Children's Hospital

Collaborators

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