# Vorinostat in Combination With Chemoradiation in Locally Advanced HPV Negative HNSCC

> **NCT05608369** · PHASE2 · WITHDRAWN · sponsor: **Case Comprehensive Cancer Center**

## Conditions studied

- HPV-Related Squamous Cell Carcinoma
- Squamous Cell Carcinoma of the Oral Cavity
- Squamous Cell Carcinoma of the Larynx
- Squamous Cell Carcinoma of the Oropharynx
- Squamous Cell Carcinoma of the Hypopharynx

## Interventions

- **DRUG:** Cisplatin
- **RADIATION:** Radiation therapy
- **DRUG:** Vorinostat

## Key facts

- **NCT ID:** NCT05608369
- **Lead sponsor:** Case Comprehensive Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2025-06-01
- **Primary completion:** 2025-08-01
- **Final completion:** 2026-02-01
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** PI left
- **Last updated:** 2025-04-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05608369

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05608369, "Vorinostat in Combination With Chemoradiation in Locally Advanced HPV Negative HNSCC". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05608369. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*