# The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial

> **NCT05618353** · PHASE4 · RECRUITING · sponsor: **VA Office of Research and Development** · enrollment: 700 (estimated)

## Conditions studied

- Coronary Artery Disease

## Interventions

- **DRUG:** Colchicine
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05618353
- **Lead sponsor:** VA Office of Research and Development
- **Sponsor class:** FED
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-08-21
- **Primary completion:** 2028-07-31
- **Final completion:** 2029-04-30
- **Target enrollment:** 700 (ESTIMATED)
- **Last updated:** 2026-04-22

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05618353

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05618353, "The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT05618353. Licensed CC0.

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