# Proton Beam Radiotherapy Followed by Tecentriq and Avastin for Primary Liver Cancer With Vp2-4 Portal Vein Invasion

> **NCT05625893** · PHASE2 · COMPLETED · sponsor: **Samsung Medical Center** · enrollment: 63 (actual)

## Conditions studied

- Hepatocellular Carcinoma
- Portal Vein Thrombosis

## Interventions

- **RADIATION:** PBT and atezolizumab/bevacizumab

## Key facts

- **NCT ID:** NCT05625893
- **Lead sponsor:** Samsung Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-01-15
- **Primary completion:** 2025-11-30
- **Final completion:** 2026-03-30
- **Target enrollment:** 63 (ACTUAL)
- **Last updated:** 2026-04-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05625893

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05625893, "Proton Beam Radiotherapy Followed by Tecentriq and Avastin for Primary Liver Cancer With Vp2-4 Portal Vein Invasion". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT05625893. Licensed CC0.

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