FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

NCT05627635 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

ACTIVE_NOT_RECRUITING

Status

20

Enrollment

OTHER

Sponsor class

Conditions

Metastatic Colon Adenocarcinoma
Metastatic Colorectal Adenocarcinoma
Metastatic Microsatellite Stable Colorectal Carcinoma
Metastatic Rectal Adenocarcinoma
Stage IV Colon Cancer AJCC v8
Stage IV Colorectal Cancer AJCC v8
Stage IV Rectal Cancer AJCC v8

Interventions

BIOLOGICAL: Balstilimab
BIOLOGICAL: Bevacizumab
PROCEDURE: Biospecimen Collection
BIOLOGICAL: Botensilimab
PROCEDURE: Computed Tomography
DRUG: Fluorouracil
DRUG: Leucovorin Calcium
PROCEDURE: Magnetic Resonance Imaging
DRUG: Oxaliplatin
PROCEDURE: Positron Emission Tomography
PROCEDURE: X-Ray Imaging

Sponsor

City of Hope Medical Center

Collaborators

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