# Primary carE PPi dEprescRibing Trial

> **NCT05629143** · PHASE4 · ACTIVE_NOT_RECRUITING · sponsor: **Universitaire Ziekenhuizen KU Leuven** · enrollment: 724 (estimated)

## Conditions studied

- Heartburn
- Dyspepsia
- Reflux

## Interventions

- **PROCEDURE:** de-prescription of PPI via intermittent scheme
- **PROCEDURE:** de-prescription of PPI via on-demand scheme
- **DRUG:** Alginate

## Key facts

- **NCT ID:** NCT05629143
- **Lead sponsor:** Universitaire Ziekenhuizen KU Leuven
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2023-05-12
- **Primary completion:** 2026-03-01
- **Final completion:** 2026-06-01
- **Target enrollment:** 724 (ESTIMATED)
- **Last updated:** 2025-01-31


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05629143

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05629143, "Primary carE PPi dEprescRibing Trial". Retrieved via AI Analytics 2026-07-27 from https://api.ai-analytics.org/clinical/NCT05629143. Licensed CC0.

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