# Biomarkers of Sleep-wake Cycle in Prodromal Alzheimer's Disease: Role in Cognitive Decline?

> **NCT05629871** · NA · RECRUITING · sponsor: **University Hospital, Montpellier** · enrollment: 132 (estimated)

## Conditions studied

- Neuropathology

## Interventions

- **PROCEDURE:** Polysomnography
- **BEHAVIORAL:** Neuropsychological assessment
- **BEHAVIORAL:** Questionnaires on sleep and behavioural problems
- **PROCEDURE:** Actimetry
- **DIAGNOSTIC_TEST:** Fractional diuresis
- **PROCEDURE:** Internal temperature measurement
- **OTHER:** Biomarker assay

## Key facts

- **NCT ID:** NCT05629871
- **Lead sponsor:** University Hospital, Montpellier
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-04-17
- **Primary completion:** 2027-07-01
- **Final completion:** 2027-07-01
- **Target enrollment:** 132 (ESTIMATED)
- **Last updated:** 2025-10-07

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05629871

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05629871, "Biomarkers of Sleep-wake Cycle in Prodromal Alzheimer's Disease: Role in Cognitive Decline?". Retrieved via AI Analytics 2026-07-01 from https://api.ai-analytics.org/clinical/NCT05629871. Licensed CC0.

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