# Study on Safety and Efficacy of NMS-01940153E in Adult Patients With Unresectable Hepatocellular Carcinoma (HCC) Previously Treated With Systemic Therapy

> **NCT05630937** · PHASE1,PHASE2 · TERMINATED · sponsor: **Nerviano Medical Sciences** · enrollment: 31 (actual)

## Conditions studied

- Unresectable Hepatocellular Carcinoma (HCC)

## Interventions

- **DRUG:** NMS-01940153E

## Key facts

- **NCT ID:** NCT05630937
- **Lead sponsor:** Nerviano Medical Sciences
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2020-11-13
- **Primary completion:** 2024-01-31
- **Final completion:** 2024-08-06
- **Target enrollment:** 31 (ACTUAL)
- **Why stopped:** In the Phase II part of the study, among the participants evaluable for efficacy, no objective (partial response or clinical response) was observed at the first futility analysis.
- **Last updated:** 2025-06-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05630937

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05630937, "Study on Safety and Efficacy of NMS-01940153E in Adult Patients With Unresectable Hepatocellular Carcinoma (HCC) Previously Treated With Systemic Therapy". Retrieved via AI Analytics 2026-06-04 from https://api.ai-analytics.org/clinical/NCT05630937. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*