CAR-DC Vaccine and ICIs in Local Advanced/Metastatic Solid Tumors

NCT05631899 · clinicaltrials.gov ↗

PHASE1

Phase

ACTIVE_NOT_RECRUITING

Status

9

Enrollment

OTHER

Sponsor class

Conditions

Solid Tumor, Adult
EphA2 Overexpression
KRAS G12V
KRAS G12C
KRAS G12D

Interventions

BIOLOGICAL: KRAS-EphA-2-CAR-DC
DRUG: Abraxane
DRUG: Cyclophosphamide
DRUG: Anti-PD-1 antibody
DRUG: Anti-CTLA4 Monoclonal Antibody

Sponsor

Chinese PLA General Hospital

Collaborators

Zhejiang University