# Atrial Appendage Micrograft Transplants to Assist Heart Repair After Cardiac Surgery

> **NCT05632432** · NA · RECRUITING · sponsor: **Hospital District of Helsinki and Uusimaa** · enrollment: 50 (estimated)

## Conditions studied

- Ischemic Heart Disease
- Ischemic Cardiomyopathy
- Heart Failure, Systolic
- Heart Failure NYHA Class III
- Heart Failure NYHA Class II
- Heart Failure NYHA Class IV
- Coronary Artery Disease

## Interventions

- **PROCEDURE:** Epicardial AAMs-patch transplantation
- **DIAGNOSTIC_TEST:** RNA-stabilized whole blood sampling
- **DIAGNOSTIC_TEST:** Plasma sampling
- **DIAGNOSTIC_TEST:** Transthoracic echocardiography
- **DIAGNOSTIC_TEST:** Late-gadolinium enhancement cardiac magnetic resonance imaging (LGE-CMRI)
- **OTHER:** Symptom-scaling
- **OTHER:** 6-minute walking test (6MWT)
- **DIAGNOSTIC_TEST:** Blood sampling (NT-proBNP)
- **DIAGNOSTIC_TEST:** Transesophageal echocardiography
- **PROCEDURE:** Epicardial collagen-based patch transplantation

## Key facts

- **NCT ID:** NCT05632432
- **Lead sponsor:** Hospital District of Helsinki and Uusimaa
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-04-01
- **Primary completion:** 2026-01-31
- **Final completion:** 2026-12-31
- **Target enrollment:** 50 (ESTIMATED)
- **Last updated:** 2024-04-19

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05632432

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05632432, "Atrial Appendage Micrograft Transplants to Assist Heart Repair After Cardiac Surgery". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05632432. Licensed CC0.

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