Dexamethasone, Olanzapine, Hemodynamics, and Ventilation in Cardiac Surgery

NCT05635227 · clinicaltrials.gov ↗

NA

Phase

RECRUITING

Status

1200

Enrollment

OTHER

Sponsor class

Conditions

Coronary Artery Disease
Aortic Valve Disease

Interventions

DRUG: Dexamethasone phosphate
DRUG: Isotonic sodium chloride (0.9%)
DRUG: Olanzapine 10 MG
DRUG: Placebo capsule
PROCEDURE: Flow-targeted hemodynamic management
PROCEDURE: Pressure-targeted hemodynamic management
PROCEDURE: Low tidal-volume ventilation
PROCEDURE: No ventilation

Sponsor

Rigshospitalet, Denmark