# HIgh Versus STAndard Blood Pressure Target in Hypertensive High-risk Patients Undergoing Major Abdominal Surgery

> **NCT05637606** · NA · COMPLETED · sponsor: **Humanitas Clinical and Research Center** · enrollment: 636 (actual)

## Conditions studied

- Blood Pressure
- Complication,Postoperative
- Intraoperative Hypotension

## Interventions

- **DRUG:** Ephedrine
- **DRUG:** Norepinephrine
- **DRUG:** Etilefrine Hydrochloride bolus
- **DIAGNOSTIC_TEST:** Use of pulse pressure and stroke volume variation (PPV and SVV); use of Mini Fluid Challenge (mini_FC)

## Key facts

- **NCT ID:** NCT05637606
- **Lead sponsor:** Humanitas Clinical and Research Center
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-03-06
- **Primary completion:** 2025-05-21
- **Final completion:** 2025-05-21
- **Target enrollment:** 636 (ACTUAL)
- **Last updated:** 2025-06-11

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05637606

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05637606, "HIgh Versus STAndard Blood Pressure Target in Hypertensive High-risk Patients Undergoing Major Abdominal Surgery". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT05637606. Licensed CC0.

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