# A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (HOPE Study)

> **NCT05637801** · NA · ACTIVE_NOT_RECRUITING · sponsor: **Cognito Therapeutics, Inc.** · enrollment: 670 (estimated)

## Conditions studied

- Alzheimer Disease
- Alzheimer Disease 1
- Alzheimer Disease 2
- Alzheimer Disease 3
- Alzheimer Disease, Early Onset
- Alzheimer Disease, Late Onset
- Alzheimer Disease 9
- Alzheimer Disease 4
- Alzheimer Disease 7
- Alzheimer Disease 17
- Alzheimer's Dementia Late Onset
- Alzheimer Disease 5
- Alzheimer Disease 6
- Alzheimer Disease 8
- Alzheimer Disease 10
- Alzheimer Disease 11
- Alzheimer Disease 12
- Alzheimer Disease 13
- Alzheimer Disease 14
- Alzheimer Disease 15
- Alzheimer Disease 16
- Alzheimer Disease 18
- Alzheimer Disease 19
- Dementia
- Dementia Alzheimers
- Dementia, Mild
- Dementia of Alzheimer Type
- Dementia Moderate
- Dementia Senile
- Mild Cognitive Impairment
- Mild Dementia
- MCI
- Cognitive Impairment
- Cognitive Decline
- Cognitive Impairment, Mild

## Interventions

- **DEVICE:** Spectris™ AD - Active
- **DEVICE:** Spectris™ AD - Sham

## Key facts

- **NCT ID:** NCT05637801
- **Lead sponsor:** Cognito Therapeutics, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2022-12-13
- **Primary completion:** 2026-06
- **Final completion:** 2026-07
- **Target enrollment:** 670 (ESTIMATED)
- **Last updated:** 2026-05-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05637801

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05637801, "A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (HOPE Study)". Retrieved via AI Analytics 2026-06-04 from https://api.ai-analytics.org/clinical/NCT05637801. Licensed CC0.

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