# Deep Phenotyping of Bone Disease in Type 2 Diabetes and Relations to Diabetic Neuropathy

> **NCT05642143** · — · UNKNOWN · sponsor: **Aalborg University Hospital** · enrollment: 300 (estimated)

## Conditions studied

- Type 2 Diabetes
- Bone Disease
- Osteoporosis
- Diabetic Neuropathy Peripheral
- Autonomic Neuropathy, Diabetic

## Interventions

- **DIAGNOSTIC_TEST:** Dual Energy X-ray Absorbtiometry scan
- **DIAGNOSTIC_TEST:** High-resolution peripheral quantitative computed tomography
- **DIAGNOSTIC_TEST:** Microindentation
- **DIAGNOSTIC_TEST:** Thermal perception thresholds
- **DIAGNOSTIC_TEST:** Nerve conduction studies
- **DIAGNOSTIC_TEST:** Composite Autonomic Symptom Score 31
- **DIAGNOSTIC_TEST:** Skin biopsies with quantification of intra-epidermal nerve fibre density
- **DIAGNOSTIC_TEST:** Perception Threshold Tracking
- **DIAGNOSTIC_TEST:** Assessment of cardiovascular autonomic neuropathy
- **DIAGNOSTIC_TEST:** Handgrip strength
- **DIAGNOSTIC_TEST:** Force plate platform
- **DIAGNOSTIC_TEST:** Biospecimen collection
- **DIAGNOSTIC_TEST:** Isometric leg extension strength
- **DIAGNOSTIC_TEST:** Michigan Neuropathy Screening Instrument

## Key facts

- **NCT ID:** NCT05642143
- **Lead sponsor:** Aalborg University Hospital
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** UNKNOWN
- **Start date:** 2023-02-24
- **Primary completion:** 2026-04
- **Final completion:** 2026-04
- **Target enrollment:** 300 (ESTIMATED)
- **Last updated:** 2024-02-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05642143

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05642143, "Deep Phenotyping of Bone Disease in Type 2 Diabetes and Relations to Diabetic Neuropathy". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05642143. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*