# Functional Near-Infrared Spectroscopy (fNIRS) Combined With Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical Controls

> **NCT05642221** · — · COMPLETED · sponsor: **Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)** · enrollment: 73 (actual)

## Conditions studied

- Juvenile Neuronal Ceroid Lipofuscinosis
- Smith-Lemli-Opitz Syndrome
- Creatine Transporter Deficiency
- Niemann-Pick Disease Type C1

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT05642221
- **Lead sponsor:** Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- **Sponsor class:** NIH
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2023-01-23
- **Primary completion:** 2024-10-10
- **Final completion:** 2025-04-25
- **Target enrollment:** 73 (ACTUAL)
- **Last updated:** 2026-04-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05642221

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05642221, "Functional Near-Infrared Spectroscopy (fNIRS) Combined With Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical Controls". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05642221. Licensed CC0.

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