# TNT of SCRT+CAPOX vs SCRT+CAPOXIRI for Locally Advanced Rectal Cancer

> **NCT05646511** · PHASE3 · RECRUITING · sponsor: **National Cancer Center Hospital East** · enrollment: 608 (estimated)

## Conditions studied

- Locally Advanced Rectal Cancer

## Interventions

- **RADIATION:** SCRT
- **DRUG:** CAPOX
- **DRUG:** CAPOXIRI

## Key facts

- **NCT ID:** NCT05646511
- **Lead sponsor:** National Cancer Center Hospital East
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-11-21
- **Primary completion:** 2029-12-31
- **Final completion:** 2030-12-31
- **Target enrollment:** 608 (ESTIMATED)
- **Last updated:** 2025-04-03

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05646511

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05646511, "TNT of SCRT+CAPOX vs SCRT+CAPOXIRI for Locally Advanced Rectal Cancer". Retrieved via AI Analytics 2026-07-17 from https://api.ai-analytics.org/clinical/NCT05646511. Licensed CC0.

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