# A Research Study to See How Semaglutide Helps People With Excess Weight, Lose Weight (STEP UP)

> **NCT05646706** · PHASE3 · COMPLETED · sponsor: **Novo Nordisk A/S** · enrollment: 1407 (actual)

## Conditions studied

- Obesity

## Interventions

- **DRUG:** Semaglutide
- **DRUG:** Semaglutide
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05646706
- **Lead sponsor:** Novo Nordisk A/S
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-01-04
- **Primary completion:** 2024-10-30
- **Final completion:** 2024-11-26
- **Target enrollment:** 1407 (ACTUAL)
- **Last updated:** 2026-04-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05646706

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05646706, "A Research Study to See How Semaglutide Helps People With Excess Weight, Lose Weight (STEP UP)". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT05646706. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*