# Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects

> **NCT05653258** · PHASE2,PHASE3 · RECRUITING · sponsor: **Cedars-Sinai Medical Center** · enrollment: 160 (estimated)

## Conditions studied

- Obesity
- Healthy Lifestyle

## Interventions

- **OTHER:** Lifestyle Intervention
- **DRUG:** Dasatinib 100 MG
- **DRUG:** Quercetin 1000mg
- **DRUG:** Placebo
- **PROCEDURE:** Abdominal adipose tissue biopsy

## Key facts

- **NCT ID:** NCT05653258
- **Lead sponsor:** Cedars-Sinai Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-10-17
- **Primary completion:** 2027-02-01
- **Final completion:** 2028-02-01
- **Target enrollment:** 160 (ESTIMATED)
- **Last updated:** 2026-03-18

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05653258

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05653258, "Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT05653258. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*