# Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis

> **NCT05663008** · — · RECRUITING · sponsor: **University of Dublin, Trinity College** · enrollment: 400 (estimated)

## Conditions studied

- ALS (Amyotrophic Lateral Sclerosis)
- Postpoliomyelitis Syndrome
- Spinal Muscular Atrophy

## Interventions

- **PROCEDURE:** 128 electrode electroencephalography (EEG), Bipolar surface electromyography (sEMG), High-density electromyography (HD-EMG)

## Key facts

- **NCT ID:** NCT05663008
- **Lead sponsor:** University of Dublin, Trinity College
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2015-10-01
- **Primary completion:** 2027-01-30
- **Final completion:** 2027-09-30
- **Target enrollment:** 400 (ESTIMATED)
- **Last updated:** 2022-12-23

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05663008

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05663008, "Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis". Retrieved via AI Analytics 2026-07-15 from https://api.ai-analytics.org/clinical/NCT05663008. Licensed CC0.

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