# Reduced Intensity Conditioning Regimens for Acute Myeloid Leukemia and Myelodysplastic Syndrome

> **NCT05674539** · PHASE3 · ENROLLING_BY_INVITATION · sponsor: **Union Hospital, Tongji Medical College, Huazhong University of Science and Technology** · enrollment: 200 (estimated)

## Conditions studied

- Acute Myeloid Leukemia, Adult
- Myelodysplastic Syndrome(MDS)
- Allogeneic Hematopoietic Stem Cell Transplantation

## Interventions

- **DRUG:** Fludarabine and Busulfan
- **DRUG:** Fludarabine and Melphalan

## Key facts

- **NCT ID:** NCT05674539
- **Lead sponsor:** Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2023-02-15
- **Primary completion:** 2025-12-30
- **Final completion:** 2025-12-30
- **Target enrollment:** 200 (ESTIMATED)
- **Last updated:** 2025-02-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05674539

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05674539, "Reduced Intensity Conditioning Regimens for Acute Myeloid Leukemia and Myelodysplastic Syndrome". Retrieved via AI Analytics 2026-09-26 from https://api.ai-analytics.org/clinical/NCT05674539. Licensed CC0.

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