# Allogeneic Stem Cell Transplantation vs. Conventional Therapy as Salvage Therapy for Relapsed / Progressive Patients With Multiple Myeloma After First-line Therapy

> **NCT05675319** · PHASE3 · TERMINATED · sponsor: **Universitätsklinikum Hamburg-Eppendorf** · enrollment: 28 (actual)

## Conditions studied

- Multiple Myeloma

## Interventions

- **DRUG:** Allogeneic Stem Cells
- **DRUG:** carfilzomib/lenalidomide/dexamethasone (KRD)
- **DRUG:** elotuzumab/lenalidomide/dexamethasone (ERD)
- **DRUG:** daratumumab/bortezomib/dexamethasone (DVD)
- **DRUG:** daratumumab/lenalidomide/dexamethasone (DRD)
- **DRUG:** ixazomib/lenalidomide/dexamethasone (IRD)
- **DRUG:** pomalidomide/bortezomib/dexamethasone (PVD)
- **DRUG:** carfilzomib/daratumumab/dexamethasone (KDD)
- **DRUG:** Autologous Stem Cells
- **DRUG:** daratumumab/pomalidomide/dexamethasone (DPD)
- **DRUG:** isatuximab/carfilzomib/dexamethasone (Isa-KD)
- **DRUG:** selinexor/bortezomib/dexamethasone (SVD)

## Key facts

- **NCT ID:** NCT05675319
- **Lead sponsor:** Universitätsklinikum Hamburg-Eppendorf
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2023-03-03
- **Primary completion:** 2025-03-14
- **Final completion:** 2025-03-21
- **Target enrollment:** 28 (ACTUAL)
- **Why stopped:** The reason for the end of recruitment is that the recruitment target could not be achieved despite all efforts and the G-BA (financing party) does not consider a continuation of the AlloRelapseMM study to be expedient.
- **Last updated:** 2026-01-05

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05675319

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05675319, "Allogeneic Stem Cell Transplantation vs. Conventional Therapy as Salvage Therapy for Relapsed / Progressive Patients With Multiple Myeloma After First-line Therapy". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05675319. Licensed CC0.

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