# Evaluation of the Effect of Systemic Proteolytic Enzyme Therapy on Postoperative Inflammatory Response and QoL After Surgical Extraction of Impacted Mandibular Third Molars

> **NCT05681312** · PHASE3 · RECRUITING · sponsor: **University of Baghdad** · enrollment: 55 (estimated)

## Conditions studied

- Post Operative Pain

## Interventions

- **DRUG:** systemic proteolytic enzyme (Tibrolin)
- **DRUG:** Amoxicillin 500mg+metronidazole 500mg+ doliprane 100mg

## Key facts

- **NCT ID:** NCT05681312
- **Lead sponsor:** University of Baghdad
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-05-08
- **Primary completion:** 2024-09-01
- **Final completion:** 2024-09-09
- **Target enrollment:** 55 (ESTIMATED)
- **Last updated:** 2024-05-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05681312

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05681312, "Evaluation of the Effect of Systemic Proteolytic Enzyme Therapy on Postoperative Inflammatory Response and QoL After Surgical Extraction of Impacted Mandibular Third Molars". Retrieved via AI Analytics 2026-06-30 from https://api.ai-analytics.org/clinical/NCT05681312. Licensed CC0.

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