# E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers

> **NCT05686226** · PHASE2 · RECRUITING · sponsor: **Christian Hinrichs** · enrollment: 20 (estimated)

## Conditions studied

- Cervical Cancer
- Throat Cancer
- Oropharynx Cancer
- Anal Cancer
- Vulva Cancer
- Vaginal Cancer
- Penile Cancer
- Metastatic Cancer
- HPV-Related Malignancy
- HPV-Related Carcinoma
- HPV-Related Cervical Carcinoma
- HPV-Related Squamous Cell Carcinoma
- HPV-Related Adenocarcinoma
- HPV Positive Oropharyngeal Squamous Cell Carcinoma
- HPV-Associated Vaginal Adenocarcinoma
- HPV-Related Adenosquamous Carcinoma
- HPV-Related Endocervical Adenocarcinoma
- HPV-Related Anal Squamous Cell Carcinoma
- HPV-Related Penile Squamous Cell Carcinoma
- HPV-Related Vulvar Squamous Cell Carcinoma
- HPV Positive Rectal Squamous Cell Carcinoma

## Interventions

- **BIOLOGICAL:** E7 TCR-T cells
- **DRUG:** Aldesleukin

## Key facts

- **NCT ID:** NCT05686226
- **Lead sponsor:** Christian Hinrichs
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-03-07
- **Primary completion:** 2027-01-01
- **Final completion:** 2027-01-01
- **Target enrollment:** 20 (ESTIMATED)
- **Last updated:** 2026-02-27

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05686226

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05686226, "E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05686226. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*