# Enhancing Exercise and Psychotherapy to Treat Pain and Addiction in Adults With an Opioid Use Disorder (EXPO; R33 Phase)

> **NCT05688410** · NA · ACTIVE_NOT_RECRUITING · sponsor: **Case Western Reserve University** · enrollment: 198 (estimated)

## Conditions studied

- Opioid Use Disorder
- Pain

## Interventions

- **OTHER:** Exercise
- **BEHAVIORAL:** Psychotherapy Pain and Addiction (I-STOP)

## Key facts

- **NCT ID:** NCT05688410
- **Lead sponsor:** Case Western Reserve University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2023-02-10
- **Primary completion:** 2028-07-05
- **Final completion:** 2028-07-05
- **Target enrollment:** 198 (ESTIMATED)
- **Last updated:** 2026-03-24

## Collaborators

- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05688410

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05688410, "Enhancing Exercise and Psychotherapy to Treat Pain and Addiction in Adults With an Opioid Use Disorder (EXPO; R33 Phase)". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05688410. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
