# GOALIE: Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent RHD Trial

> **NCT05693545** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **Children's Hospital Medical Center, Cincinnati** · enrollment: 1004 (estimated)

## Conditions studied

- Rheumatic Heart Disease

## Interventions

- **DRUG:** phenoxymethyl penicillin
- **DRUG:** intramuscular benzathine penicillin G (BPG) prophylaxis

## Key facts

- **NCT ID:** NCT05693545
- **Lead sponsor:** Children's Hospital Medical Center, Cincinnati
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2023-09-01
- **Primary completion:** 2027-03-31
- **Final completion:** 2027-09-30
- **Target enrollment:** 1004 (ESTIMATED)
- **Last updated:** 2026-03-17

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05693545

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05693545, "GOALIE: Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent RHD Trial". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT05693545. Licensed CC0.

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