# Postoperative Oral Methadone After Major Spine Surgery; Safety, Feasibility and Efficacy in Prevention of Progression to Chronic Opioid Usage at 3 Months

> **NCT05693675** · PHASE2,PHASE3 · WITHDRAWN · sponsor: **The University of Texas Health Science Center, Houston**

## Conditions studied

- Spine Surgery

## Interventions

- **DRUG:** Postoperative methadone
- **DRUG:** Postoperative placebo
- **DRUG:** Rescue Analgesia

## Key facts

- **NCT ID:** NCT05693675
- **Lead sponsor:** The University of Texas Health Science Center, Houston
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2023-10-01
- **Primary completion:** 2024-07-01
- **Final completion:** 2024-07-01
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** PI left institution; no participants were enrolled
- **Last updated:** 2025-03-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05693675

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05693675, "Postoperative Oral Methadone After Major Spine Surgery; Safety, Feasibility and Efficacy in Prevention of Progression to Chronic Opioid Usage at 3 Months". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05693675. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*