# Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study

> **NCT05695027** · PHASE2,PHASE3 · ACTIVE_NOT_RECRUITING · sponsor: **Columbia University** · enrollment: 250 (estimated)

## Conditions studied

- Primary Open Angle Glaucoma

## Interventions

- **DRUG:** Dietary supplements - Nicotinamide and Pyruvate
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05695027
- **Lead sponsor:** Columbia University
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2023-03-14
- **Primary completion:** 2026-06
- **Final completion:** 2028-01
- **Target enrollment:** 250 (ESTIMATED)
- **Last updated:** 2025-11-12

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05695027

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05695027, "Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT05695027. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*