# Efficacy of Cotrimoxazole as a De-escalation Treatment of Ventilator-Associated Pneumonia in Intensive Care Unit

> **NCT05696093** · PHASE3 · RECRUITING · sponsor: **Assistance Publique - Hôpitaux de Paris** · enrollment: 628 (estimated)

## Conditions studied

- Ventilator Associated Pneumonia

## Interventions

- **DRUG:** cotrimoxazole
- **DRUG:** standard antibiotic therapy

## Key facts

- **NCT ID:** NCT05696093
- **Lead sponsor:** Assistance Publique - Hôpitaux de Paris
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-10-19
- **Primary completion:** 2026-10-31
- **Final completion:** 2026-12-31
- **Target enrollment:** 628 (ESTIMATED)
- **Last updated:** 2025-05-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05696093

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05696093, "Efficacy of Cotrimoxazole as a De-escalation Treatment of Ventilator-Associated Pneumonia in Intensive Care Unit". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT05696093. Licensed CC0.

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