# PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

> **NCT05699174** · PHASE3 · RECRUITING · sponsor: **Major Extremity Trauma Research Consortium** · enrollment: 250 (estimated)

## Conditions studied

- Infections
- Infected Wound
- Nonunion of Fracture
- Injury Leg
- Amputation
- Internal Fixation; Complications, Infection or Inflammation
- Fracture
- Lower Extremity Fracture
- Antibiotic Side Effect

## Interventions

- **DRUG:** Standard of Care PO (oral) antibiotics
- **DRUG:** Standard of Care Intravenous (IV) antibiotics

## Key facts

- **NCT ID:** NCT05699174
- **Lead sponsor:** Major Extremity Trauma Research Consortium
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-05-30
- **Primary completion:** 2026-09
- **Final completion:** 2027-09-29
- **Target enrollment:** 250 (ESTIMATED)
- **Last updated:** 2026-02-02

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05699174

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05699174, "PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05699174. Licensed CC0.

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