# A Study to Learn About a Modified RNA Vaccine Against Shingles in Healthy Adults

> **NCT05703607** · PHASE1,PHASE2 · TERMINATED · sponsor: **Pfizer** · enrollment: 484 (actual)

## Conditions studied

- Shingles
- Herpes Zoster Infection
- Human

## Interventions

- **BIOLOGICAL:** Candidate 1: PF-07915234: VZV modRNA Powder for Suspension for Injection
- **BIOLOGICAL:** Candidate 1: PF-07915234: VZV modRNA Suspension for Injection
- **BIOLOGICAL:** Candidate 2: PF-07921188: VZV modRNA Suspension for Injection
- **BIOLOGICAL:** Candidate 3: PF-07921186: VZV modRNA Suspension for Injection
- **BIOLOGICAL:** Shingrix
- **BIOLOGICAL:** Candidate 2: PF-07921188: VZV modRNA Powder for Suspension for Injection

## Key facts

- **NCT ID:** NCT05703607
- **Lead sponsor:** Pfizer
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2023-01-25
- **Primary completion:** 2025-09-23
- **Final completion:** 2025-09-23
- **Target enrollment:** 484 (ACTUAL)
- **Why stopped:** Strategic decision made by the company
- **Last updated:** 2026-05-04

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05703607

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05703607, "A Study to Learn About a Modified RNA Vaccine Against Shingles in Healthy Adults". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT05703607. Licensed CC0.

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