# A Prospective, Randomized, Clinical Study on the Effects of CPP-ACP-paste, Fluoride and a Combination on the Evolution of White Spot Lesions in Orthodontic Patients After Debonding.

> **NCT05710874** · NA · COMPLETED · sponsor: **University Hospital, Ghent** · enrollment: 107 (actual)

## Conditions studied

- White Spot Lesion
- Orthodontic Appliance Complication

## Interventions

- **OTHER:** CPP-ACP paste
- **OTHER:** CPP-ACPF paste
- **OTHER:** 1.25% fluoride gel
- **OTHER:** Conventional

## Key facts

- **NCT ID:** NCT05710874
- **Lead sponsor:** University Hospital, Ghent
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2016-09-23
- **Primary completion:** 2023-03-29
- **Final completion:** 2023-03-29
- **Target enrollment:** 107 (ACTUAL)
- **Last updated:** 2023-08-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05710874

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05710874, "A Prospective, Randomized, Clinical Study on the Effects of CPP-ACP-paste, Fluoride and a Combination on the Evolution of White Spot Lesions in Orthodontic Patients After Debonding.". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT05710874. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*