Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma

NCT05717153 · clinicaltrials.gov ↗

EARLY_PHASE1

Phase

RECRUITING

Status

18

Enrollment

OTHER

Sponsor class

Conditions

Diffuse Glioma
Malignant Glioma

Interventions

PROCEDURE: Biospecimen Collection
PROCEDURE: Computed Tomography
DRUG: Eflornithine
PROCEDURE: Magnetic Resonance Imaging
DRUG: Polyamine Transport Inhibitor AMXT-1501 Dicaprate
PROCEDURE: Resection
DEVICE: Microdialysis
PROCEDURE: Placement

Sponsor

Mayo Clinic

Collaborators

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