# Pancreatic Clamp in NAFLD

> **NCT05724134** · PHASE1 · COMPLETED · sponsor: **Columbia University** · enrollment: 18 (actual)

## Conditions studied

- Insulin Resistance
- Prediabetic State
- Hyperinsulinemia
- Non-Alcoholic Fatty Liver Disease
- Obesity

## Interventions

- **DRUG:** Insulin human
- **DRUG:** Octreotide Acetate
- **DRUG:** Glucagon
- **DRUG:** Growth Hormone, Human
- **OTHER:** [6,6-2H2] D-glucose
- **DRUG:** 20% D-glucose (aq)
- **DIETARY_SUPPLEMENT:** BOOST Plus
- **DIETARY_SUPPLEMENT:** CORE Bar
- **DEVICE:** Harvard Apparatus PHD ULTRA CP syringe pump
- **DEVICE:** Yellow Springs Instruments (YSI) 2500 Biochemistry Glucose/Lactate Analyzer

## Key facts

- **NCT ID:** NCT05724134
- **Lead sponsor:** Columbia University
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-08-29
- **Primary completion:** 2025-09-24
- **Final completion:** 2025-09-24
- **Target enrollment:** 18 (ACTUAL)
- **Last updated:** 2026-01-12

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05724134

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05724134, "Pancreatic Clamp in NAFLD". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05724134. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*