# A Pilot Study Testing the Safety and Feasibility of Restorative Microbiota Therapy (RMT) in Patients With Refractory Immune-checkpoint Inhibitor-related Colitis

> **NCT05726396** · PHASE2 · WITHDRAWN · sponsor: **University of Minnesota**

## Conditions studied

- Immune-related Colitis
- Colitis

## Interventions

- **DRUG:** RMT
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05726396
- **Lead sponsor:** University of Minnesota
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2025-09-23
- **Primary completion:** 2026-02-01
- **Final completion:** 2026-02-01
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** The trial has been on hold due to inability to finalize product procurement and testing through the FDA
- **Last updated:** 2026-02-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05726396

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05726396, "A Pilot Study Testing the Safety and Feasibility of Restorative Microbiota Therapy (RMT) in Patients With Refractory Immune-checkpoint Inhibitor-related Colitis". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT05726396. Licensed CC0.

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