# REPOSE Study: Reducing Delirium by Enhancing Postoperative Sleep With Suvorexant

> **NCT05733286** · PHASE2 · COMPLETED · sponsor: **Duke University** · enrollment: 142 (actual)

## Conditions studied

- Delirium in Old Age

## Interventions

- **DRUG:** Suvorexant 20 mg
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05733286
- **Lead sponsor:** Duke University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-06-28
- **Primary completion:** 2025-06-25
- **Final completion:** 2025-07-07
- **Target enrollment:** 142 (ACTUAL)
- **Last updated:** 2026-01-15

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05733286

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05733286, "REPOSE Study: Reducing Delirium by Enhancing Postoperative Sleep With Suvorexant". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT05733286. Licensed CC0.

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