# Puberty, Sex Hormones and Pain Sensitivity in Adolescents With Migraine

> **NCT05738213** · NA · ACTIVE_NOT_RECRUITING · sponsor: **Washington University School of Medicine** · enrollment: 100 (estimated)

## Conditions studied

- Migraine

## Interventions

- **DEVICE:** Thermal stimuli
- **DEVICE:** Pressure stimuli
- **BEHAVIORAL:** Pain ratings
- **BEHAVIORAL:** Pressure pain thresholds (PPT)
- **BEHAVIORAL:** Conditioned pain modulation (CPM) response
- **BEHAVIORAL:** PedMIDAS (Pediatric Migraine Disability Assessment)
- **DIAGNOSTIC_TEST:** Hormonal assessment
- **OTHER:** Pubertal status

## Key facts

- **NCT ID:** NCT05738213
- **Lead sponsor:** Washington University School of Medicine
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2023-01-10
- **Primary completion:** 2025-07-14
- **Final completion:** 2028-01-01
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2025-10-16

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05738213

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05738213, "Puberty, Sex Hormones and Pain Sensitivity in Adolescents With Migraine". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05738213. Licensed CC0.

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