# Improving Diagnosis and Clinical Management of Familial Hypercholesterolemia Through Integrated Machine Learning, Implementation Science, and Behavioral Economics

> **NCT05746247** · NA · ENROLLING_BY_INVITATION · sponsor: **University of Pennsylvania** · enrollment: 750 (estimated)

## Conditions studied

- Familial Hypercholesterolemia

## Interventions

- **BEHAVIORAL:** Testing centralized referral mechanism for PCPs
- **BEHAVIORAL:** Inviting patients to complete a telehealth appointment with a lipid specialist for an FH evaluation

## Key facts

- **NCT ID:** NCT05746247
- **Lead sponsor:** University of Pennsylvania
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2022-03-01
- **Primary completion:** 2026-01-31
- **Final completion:** 2026-06-30
- **Target enrollment:** 750 (ESTIMATED)
- **Last updated:** 2026-03-05

## Collaborators

- Family Heart Foundation
- Northwestern University

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05746247

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05746247, "Improving Diagnosis and Clinical Management of Familial Hypercholesterolemia Through Integrated Machine Learning, Implementation Science, and Behavioral Economics". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT05746247. Licensed CC0.

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