# Phase 1/2 Study of AOC 1020 in Participants With Facioscapulohumeral Muscular Dystrophy (FSHD)

> **NCT05747924** · PHASE1,PHASE2 · COMPLETED · sponsor: **Avidity Biosciences, Inc.** · enrollment: 90 (actual)

## Conditions studied

- FSHD
- FSHD1
- FSHD2
- FMD
- FMD2
- Fascioscapulohumeral Muscular Dystrophy
- Fascioscapulohumeral Muscular Dystrophy Type 1
- Fascioscapulohumeral Muscular Dystrophy Type 2
- Dystrophies, Facioscapulohumeral Muscular
- Dystrophy, Facioscapulohumeral Muscular
- Facioscapulohumeral Muscular Dystrophy 1
- Facioscapulohumeral Muscular Dystrophy 2
- Facio-Scapulo-Humeral Dystrophy
- Atrophy, Facioscapulohumeral
- Atrophies, Facioscapulohumeral
- Facioscapulohumeral Atrophy
- Muscular Dystrophies
- Muscular Dystrophy, Facioscapulohumeral
- FSH Muscular Dystrophy
- Landouzy Dejerine Dystrophy
- Landouzy-Dejerine Muscular Dystrophy
- Dystrophies, Landouzy-Dejerine
- Dystrophy, Landouzy-Dejerine
- Landouzy-Dejerine Syndrome
- Muscular Dystrophy, Landouzy Dejerine
- Progressive Muscular Dystrophy
- FSH

## Interventions

- **DRUG:** AOC 1020
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05747924
- **Lead sponsor:** Avidity Biosciences, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-04-04
- **Primary completion:** 2026-03-18
- **Final completion:** 2026-03-20
- **Target enrollment:** 90 (ACTUAL)
- **Last updated:** 2026-04-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05747924

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05747924, "Phase 1/2 Study of AOC 1020 in Participants With Facioscapulohumeral Muscular Dystrophy (FSHD)". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05747924. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*