# An Open-Label Exploratory Study of Fosigotifator in Participants With Vanishing White Matter Disease

> **NCT05757141** · PHASE1,PHASE2 · RECRUITING · sponsor: **Calico Life Sciences LLC** · enrollment: 50 (estimated)

## Conditions studied

- Vanishing White Matter Disease

## Interventions

- **DRUG:** Fosigotifator

## Key facts

- **NCT ID:** NCT05757141
- **Lead sponsor:** Calico Life Sciences LLC
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-03-13
- **Primary completion:** 2027-11
- **Final completion:** 2029-11
- **Target enrollment:** 50 (ESTIMATED)
- **Last updated:** 2025-11-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05757141

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05757141, "An Open-Label Exploratory Study of Fosigotifator in Participants With Vanishing White Matter Disease". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05757141. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*