# Perioperative Nitric Oxide Prevents Acute Kidney Injury in Cardiac Surgery Patients With Chronic Kidney Disease

> **NCT05757557** · PHASE1,PHASE2 · COMPLETED · sponsor: **Tomsk National Research Medical Center of the Russian Academy of Sciences** · enrollment: 136 (actual)

## Conditions studied

- Acute Kidney Disease
- Chronic Kidney Disease
- Cardiac Surgery
- Cardiopulmonary Bypass

## Interventions

- **DRUG:** Sham treatment
- **DRUG:** 80-ppm NO

## Key facts

- **NCT ID:** NCT05757557
- **Lead sponsor:** Tomsk National Research Medical Center of the Russian Academy of Sciences
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-02-25
- **Primary completion:** 2024-12-31
- **Final completion:** 2025-01-31
- **Target enrollment:** 136 (ACTUAL)
- **Last updated:** 2025-04-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05757557

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05757557, "Perioperative Nitric Oxide Prevents Acute Kidney Injury in Cardiac Surgery Patients With Chronic Kidney Disease". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05757557. Licensed CC0.

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