# The Potential of Oxytocin to Reduce Opioid Abuse Liability and Pain Among Older Adults

> **NCT05761860** · EARLY_PHASE1 · RECRUITING · sponsor: **University of Florida** · enrollment: 45 (estimated)

## Conditions studied

- Pain

## Interventions

- **DRUG:** OxyCODONE 5 mg Oral Tablet
- **DRUG:** OxyCODONE 2.5 mg Oral Tablet
- **OTHER:** Placebo oxyCODONE Oral Tablet
- **DRUG:** Oxytocin Nasal Spray (48 IU)
- **OTHER:** Placebo Oxytocin Nasal Spray

## Key facts

- **NCT ID:** NCT05761860
- **Lead sponsor:** University of Florida
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-09-12
- **Primary completion:** 2026-12
- **Final completion:** 2027-07
- **Target enrollment:** 45 (ESTIMATED)
- **Last updated:** 2026-05-01

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05761860

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05761860, "The Potential of Oxytocin to Reduce Opioid Abuse Liability and Pain Among Older Adults". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05761860. Licensed CC0.

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