# DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers.

> **NCT05770544** · PHASE2,PHASE3 · RECRUITING · sponsor: **Cancer Research UK** · enrollment: 30 (estimated)

## Conditions studied

- Haematological Malignancy
- Malignancy
- Malignant Neoplasm
- Lymphoproliferative Disorders
- Neoplasms by Histologic Type
- Neoplasms by Site
- Cancer
- Brain Neoplasms
- Melanoma
- Glioma
- Solid Tumour

## Interventions

- **DRUG:** Entrectinib

## Key facts

- **NCT ID:** NCT05770544
- **Lead sponsor:** Cancer Research UK
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-11-30
- **Primary completion:** 2029-10
- **Final completion:** 2029-10
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2025-11-24

## Collaborators

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- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05770544

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05770544, "DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers.". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT05770544. Licensed CC0.

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