# A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (B)

> **NCT05771402** · PHASE2 · RECRUITING · sponsor: **The Second Affiliated Hospital of Chongqing Medical University** · enrollment: 120 (estimated)

## Conditions studied

- Chronic Hepatitis b
- Anti-PD-1 Antibody
- Peg-IFNα

## Interventions

- **DRUG:** Anti-PD-1 antibody
- **DRUG:** NAs
- **DRUG:** Peg-IFNα

## Key facts

- **NCT ID:** NCT05771402
- **Lead sponsor:** The Second Affiliated Hospital of Chongqing Medical University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-10-10
- **Primary completion:** 2026-12-31
- **Final completion:** 2026-12-31
- **Target enrollment:** 120 (ESTIMATED)
- **Last updated:** 2025-09-11

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05771402

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05771402, "A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (B)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05771402. Licensed CC0.

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