# Efficacy and Safety of AC102 Compared to Steroids in Adults With Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL)

> **NCT05776459** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **AudioCure Pharma GmbH** · enrollment: 210 (estimated)

## Conditions studied

- Hearing Loss, Sensorineural

## Interventions

- **DRUG:** AC102 gel
- **DRUG:** Prednisolone
- **OTHER:** Placebo Tablets
- **OTHER:** Placebo gel

## Key facts

- **NCT ID:** NCT05776459
- **Lead sponsor:** AudioCure Pharma GmbH
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2022-10-13
- **Primary completion:** 2026-02-28
- **Final completion:** 2026-07-31
- **Target enrollment:** 210 (ESTIMATED)
- **Last updated:** 2026-01-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05776459

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05776459, "Efficacy and Safety of AC102 Compared to Steroids in Adults With Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05776459. Licensed CC0.

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