# Role of NAC in cT0 Muscle-invasive Bladder Cancer After Maximal TURBt

> **NCT05776758** · PHASE3 · ACTIVE_NOT_RECRUITING · sponsor: **Regina Elena Cancer Institute** · enrollment: 236 (estimated)

## Conditions studied

- Muscle-Invasive Bladder Carcinoma
- Chemotherapy Effect
- Surgery

## Interventions

- **DRUG:** cisplatin based neoadjuvant chemotherapy
- **PROCEDURE:** Radical cystectomy alone

## Key facts

- **NCT ID:** NCT05776758
- **Lead sponsor:** Regina Elena Cancer Institute
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2024-11-29
- **Primary completion:** 2026-01
- **Final completion:** 2027-01
- **Target enrollment:** 236 (ESTIMATED)
- **Last updated:** 2025-04-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05776758

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05776758, "Role of NAC in cT0 Muscle-invasive Bladder Cancer After Maximal TURBt". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT05776758. Licensed CC0.

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