# Low-dose Buprenorphine as a Modulator of Social Motivation in Schizophrenia

> **NCT05778591** · PHASE2 · RECRUITING · sponsor: **University of California, Los Angeles** · enrollment: 40 (estimated)

## Conditions studied

- Schizophrenia

## Interventions

- **DRUG:** Placebo
- **DRUG:** Buprenorphine 0.15 MG [Belbuca]

## Key facts

- **NCT ID:** NCT05778591
- **Lead sponsor:** University of California, Los Angeles
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-05-17
- **Primary completion:** 2026-12-01
- **Final completion:** 2027-03-01
- **Target enrollment:** 40 (ESTIMATED)
- **Last updated:** 2026-04-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05778591

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05778591, "Low-dose Buprenorphine as a Modulator of Social Motivation in Schizophrenia". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT05778591. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*